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  • What is Fetal Bovine Serum

    Fetal bovine serum (FBS) is the liquid fraction remaining after the blood drawn from bovine fetus coagulates. 1 Through centrifugation, cells, coagulation fibrinogens, and proteins are removed to produce serum. Although fetal bovine serum has cells and clotting factors removed, over a thousand components conducive to cell growth remain, including:

    Get Price
  • Alternative to FBS in animal cell culture - An overview ...

    2021-8-1u2002·u2002Fetal bovine serum (FBS) is a widely used growth supplement in the in vitro culturing of animal and human cells, tissues and organs, notably due to the occurrence of abundant micro- and macronutrients, along with growth factors. Over the years, increasing demand, high price, batch-to-batch variability in quality and composition, increasing ...

    Get Price
  • B3 Commercial collection of fetal bovine serum

    2019-5-2u2002·u2002Fetal bovine serum is a biological product obtained from the blood of fetal calves. Serum is the component of blood left after the red blood cells have been removed (the blood is allowed to clot, the tubes are centrifuged and the serum is pipetted off). Because fetal bovine serum promotes cell growth and cell proliferation, it has

    Get Price
  • FastGro Synthetic, chemically defined FBS replacement ...

    FastGro allows culturing cells in vitro without the use of serum and without any animal or human derived compound. FastGro is a fully defined additive, avoiding the need for serum, for a wide range of cell culture practices. Since FastGro is chemically defined it avoids lot-to-lot variations. All components in FastGro are highly purified and identified chemical compounds.

    FastGro is ...

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  • Serum-free cell culture: the serum-free media interactive ...

    Fetal bovine serum (FBS) is a ubiquitously used essential supplement in cell culture media. However, there are serious scientific and ethical concerns about the use of FBS regarding its harvest and production. During the last three decades, FBS could be substituted by other supplements or by the use …

    Get Price
  • Serum: A Better Characterized Biological

    2019-8-28u2002·u2002International Serum Industry Association McHenry, MD Serum: A Better Characterized Biological Abstract The International Serum Industry Association (ISIA) was founded in 2006 to represent collectors, producers, suppliers, distributors, and end-users of animal serum and other animal-derived materials worldwide.

    Get Price
  • Knock-Out Serum Replacement and Melatonin Effects on

    2017-8-25u2002·u2002AlbuMAX as replacement for fetal calf or fetal bovine serum.9,14,16 To date, the culture conditions described by Sato and colleagues in 2011 have been applied to different settings including cryopreserved murine testicular tis-sue,7,38 adult murine testicular tissue,24 single cell sus-pensions obtained from juvenile murine testis,25 juvenile ...

    Get Price
  • The Replacement of Fetal Bovine Serum with Bovine Serum ...

    2020-6-12u2002·u2002Bovine serum albumin (BSA) is a source of protein that can be used as an alternative to embryo culture, considering that free fetal bovine serum (FBS) systems increase embryo cryotolerance. 18 Although there have been several studies using BSA supplementation in embryo culture media, 20,21 studies carried out with both steps, in vitro ...

    Get Price
  • What is Fetal Bovine Serum

    Fetal bovine serum (FBS) is the liquid fraction remaining after the blood drawn from bovine fetus coagulates. 1 Through centrifugation, cells, coagulation fibrinogens, and proteins are removed to produce serum. Although fetal bovine serum has cells and clotting factors removed, over a thousand components conducive to cell growth remain, including:

    Get Price
  • Alternative to FBS in animal cell culture - An overview ...

    2021-8-1u2002·u2002Fetal bovine serum (FBS) is a widely used growth supplement in the in vitro culturing of animal and human cells, tissues and organs, notably due to the occurrence of abundant micro- and macronutrients, along with growth factors. Over the years, increasing demand, high price, batch-to-batch variability in quality and composition, increasing ...

    Get Price
  • B3 Commercial collection of fetal bovine serum

    2019-5-2u2002·u2002Fetal bovine serum is a biological product obtained from the blood of fetal calves. Serum is the component of blood left after the red blood cells have been removed (the blood is allowed to clot, the tubes are centrifuged and the serum is pipetted off). Because fetal bovine serum promotes cell growth and cell proliferation, it has

    Get Price
  • Molecular Characterization of Pestiviruses in Fetal Bovine ...

    2019-10-16u2002·u2002Serological evidence suggests that HoBi-like viruses, an emerging species within the Pestivirus genus of the Flaviviridae family, are in circulation in Argentina. While HoBi-like viruses were first isolated from Brazilian fetal bovine serum (FBS), no survey of Argentine FBS has been conducted. Therefore, 124 local samples of non-irradiated FBS originating from Argentina were …

    Get Price
  • FastGro Synthetic, chemically defined FBS replacement ...

    FastGro allows culturing cells in vitro without the use of serum and without any animal or human derived compound. FastGro is a fully defined additive, avoiding the need for serum, for a wide range of cell culture practices. Since FastGro is chemically defined it avoids lot-to-lot variations. All components in FastGro are highly purified and identified chemical compounds.

    Get Price

  • Serum-free cell culture: the serum-free media interactive ...

    Fetal bovine serum (FBS) is a ubiquitously used essential supplement in cell culture media. However, there are serious scientific and ethical concerns about the use of FBS regarding its harvest and production. During the last three decades, FBS could be substituted by other supplements or by the use …

    Get Price
  • Serum: A Better Characterized Biological

    2019-8-28u2002·u2002International Serum Industry Association McHenry, MD Serum: A Better Characterized Biological Abstract The International Serum Industry Association (ISIA) was founded in 2006 to represent collectors, producers, suppliers, distributors, and end-users of animal serum and other animal-derived materials worldwide.

    Get Price
  • Knock-Out Serum Replacement and Melatonin Effects on Germ ...

    2017-8-25u2002·u2002AlbuMAX as replacement for fetal calf or fetal bovine serum.9,14,16 To date, the culture conditions described by Sato and colleagues in 2011 have been applied to different settings including cryopreserved murine testicular tis-sue,7,38 adult murine testicular tissue,24 single cell sus-pensions obtained from juvenile murine testis,25 juvenile ...

    Get Price
  • Health Ministry, Bharat Biotech Deny Covaxin Has New Born ...

    2021-6-16u2002·u2002New born calf serum is also a cost-effective replacement to fetal bovine serum and is more easily available. A research paper highlighted that new born calf serum is a cheaper substitute to fetal calf serum as it impacts the growth and maturation of cells as effectively as fetal cells do.

    Get Price
  • Fetal Bovine Serum Global Market Report 2021: COVID-19 ...

    2021-7-9u2002·u2002The global fetal bovine serum market is expected to grow from $855.80 million in 2020 to $946.25 million in 2021 at a compound annual growth rate (CAGR) of 10.6%. The growth in mainly due to increase in R&D towards development of novel biopharmaceuticals. The market is expected to reach $1,175.36 million in 2025 at a CAGR of 5.6%.

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  • EquaFETAL® Bovine Serum - Aseptically Filled - Heat ...

    2021-9-16u2002·u2002EquaFETAL® Bovine Serum – Aseptically Filled – Heat Inactivated. £ 298.52. Equafoetal is an FBS equivalent developed to reduce batch-to-batch variation of FBS. It is composed of bovine serum and has been developed to offer a cost effective alternative to FBS. Equafoetal is 100% US origin and may be used to replace US origin in situations ...

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  • Tribological performances of symmetrically micro-textured ...

    2020-9-15u2002·u2002The tribological test was performed under fetal bovine serum available from HiMedia Laboratory Pvt. Ltd. (Product code # RM10432-100 mL, Brazil Origin). The Serum has a total Protein concentration of 3-4.5 g/dl and viscosity of 4.9 cPs at a temperature of 20 °C as per the manufacturer certification.

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  • Effect of serum replacement on murine spermatogonial stem ...

    2021-1-1u2002·u2002Fetal bovine serum (FBS; Biowest, Nuaillé, France) was added at a final concentration of 10% to inactivate the enzyme. The cell suspension was filtered through a nylon mesh with a 40-μm pore size (BD Biosciences, San Jose, CA, USA) to remove debris after digestion and centrifuged at 600 × g at 4°C for 7 min.

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  • A consensus introduction to serum replacements and serum ...

    2017-2-1u2002·u2002The most common type of serum used in the cell therapy industry is fetal bovine serum (FBS). The U.S. Food and Drug Administration (FDA) recently noted that more than 80% of the 66 investigational new drug applications for mesenchymal stromal cell (MSC) products analyzed described the use of FBS during manufacturing [4] .

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  • Stem Cell–Derived Bioactive Materials Accelerate ...

    2015-6-1u2002·u2002Stem cells show the capability to proliferate in an undifferentiated state with long-term self-renewal, which gives the cells advantages for use as bioactive material (BM) for embryo culture in vitro.The objective of this experiment was to investigate the effect of two BMs—human adipose tissue–derived mesenchymal stem cell BM (hAT-MSC-BM) and human embryonic stem …

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  • Improved In Vitro Culture Conditions to Enhance the ...

    2010-8-1u2002·u2002The overgrowth of testicular somatic cells could be suppressed by adjusting fetal bovine serum concentration in the medium to 1%. The addition of soluble factors, such as bovine serum albumin, adenosine, and salmonid serum, to the medium would enhance spermatogonial survival, mitotic activity, and transplantability.

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  • Cytiva

    Cytiva is a global provider of technologies and services that help advance and accelerate the development and manufacture of therapeutics. With a heritage of innovation, they continue to move forward, building on the brands you've come to rely on for quality and reliability. Their diverse portfolio includes the well-recognized ÄKTA ...

    Get Price
  • Plant-based and cell-based approaches to meat production ...

    2020-12-8u2002·u2002In 2003, it was estimated that blood from 1,000,000 bovine fetuses was harvested to generate the annual production of 500,000 liters of fetal bovine serum 81. Serum …

    Get Price
  • Differentiation of HL-60 cells in serum-free hematopoietic ...

    2021-2-11u2002·u2002High concentrations of serum have been reported to inhibit differentiation . X-VIVO™ 15 is a serum-free medium, which has been reported to improve cell differentiation . Hence, the effects of serum (RPMI-1640 supplemented with 10% FBS) and serum-free medium (X-VIVO™ 15 medium) on the differentiation of HL-60 cells were also compared.

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  • The Replacement of Fetal Bovine Serum with Bovine Serum ...

    2020-6-12u2002·u2002Bovine serum albumin (BSA) is a source of protein that can be used as an alternative to embryo culture, considering that free fetal bovine serum (FBS) systems increase embryo cryotolerance. 18 Although there have been several studies using BSA supplementation in embryo culture media, 20,21 studies carried out with both steps, in vitro ...

    Get Price
  • What is Fetal Bovine Serum

    Fetal bovine serum (FBS) is the liquid fraction remaining after the blood drawn from bovine fetus coagulates. 1 Through centrifugation, cells, coagulation fibrinogens, and proteins are removed to produce serum. Although fetal bovine serum has cells and clotting factors removed, over a thousand components conducive to cell growth remain, including:

    Get Price
  • Alternative to FBS in animal cell culture - An overview ...

    2021-8-1u2002·u2002Fetal bovine serum (FBS) is a widely used growth supplement in the in vitro culturing of animal and human cells, tissues and organs, notably due to the occurrence of abundant micro- and macronutrients, along with growth factors. Over the years, increasing demand, high price, batch-to-batch variability in quality and composition, increasing ...

    Get Price
  • B3 Commercial collection of fetal bovine serum

    2019-5-2u2002·u2002Fetal bovine serum is a biological product obtained from the blood of fetal calves. Serum is the component of blood left after the red blood cells have been removed (the blood is allowed to clot, the tubes are centrifuged and the serum is pipetted off). Because fetal bovine serum promotes cell growth and cell proliferation, it has

    Get Price
  • Molecular Characterization of Pestiviruses in Fetal Bovine ...

    2019-10-16u2002·u2002Serological evidence suggests that HoBi-like viruses, an emerging species within the Pestivirus genus of the Flaviviridae family, are in circulation in Argentina. While HoBi-like viruses were first isolated from Brazilian fetal bovine serum (FBS), no survey of Argentine FBS has been conducted. Therefore, 124 local samples of non-irradiated FBS originating from …

    Get Price
  • FastGro Synthetic, chemically defined FBS replacement ...

    FastGro allows culturing cells in vitro without the use of serum and without any animal or human derived compound. FastGro is a fully defined additive, avoiding the need for serum, for a wide range of cell culture practices. Since FastGro is chemically defined it avoids lot-to-lot variations. All components in FastGro are highly purified and identified chemical compounds.

    Get Price

  • Serum-free cell culture: the serum-free media interactive ...

    Fetal bovine serum (FBS) is a ubiquitously used essential supplement in cell culture media. However, there are serious scientific and ethical concerns about the use of FBS regarding its harvest and production. During the last three decades, FBS could be substituted by other supplements or by the use …

    Get Price
  • Serum: A Better Characterized Biological

    2019-8-28u2002·u2002International Serum Industry Association McHenry, MD Serum: A Better Characterized Biological Abstract The International Serum Industry Association (ISIA) was founded in 2006 to represent collectors, producers, suppliers, distributors, and end-users of animal serum and other animal-derived materials worldwide.

    Get Price
  • Knock-Out Serum Replacement and Melatonin Effects

    2017-8-25u2002·u2002AlbuMAX as replacement for fetal calf or fetal bovine serum.9,14,16 To date, the culture conditions described by Sato and colleagues in 2011 have been applied to different settings including cryopreserved murine testicular tis-sue,7,38 adult murine testicular tissue,24 single cell sus-pensions obtained from juvenile murine testis,25 juvenile ...

    Get Price
  • Health Ministry, Bharat Biotech Deny Covaxin Has New

    2021-6-16u2002·u2002New born calf serum is also a cost-effective replacement to fetal bovine serum and is more easily available. A research paper highlighted that new born calf serum is a cheaper substitute to fetal calf serum as it impacts the growth and maturation of cells as effectively as fetal …

    Get Price
  • Plant-based and cell-based approaches to meat production

    2020-12-8u2002·u2002Fetal bovine serum is a common additive to cell culture media and it provides essential growth factors for mammalian cell culture. In 2003, it was estimated that blood from 1,000,000 bovine fetuses was harvested to generate the annual production of 500,000 liters of fetal bovine serum 81. Serum-free alternatives include co-culture approaches or ...

    Get Price
  • Plant-based and cell-based approaches to meat

    2020-12-8u2002·u2002In 2003, it was estimated that blood from 1,000,000 bovine fetuses was harvested to generate the annual production of 500,000 liters of fetal bovine serum 81. Serum-free alternatives include co ...

    Get Price
  • What are the best animal-free alternatives to FBS/FCS in ...

    Stocks of fetal bovine serum (FBS) - an essential active substance in cell culture - are low. New EU directives on meat imports, the weak US dollar and cultivation of energy crops have changed the ...

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  • Genetic and functional diversification of chemosensory ...

    2020-6-8u2002·u2002pahangi L3s freshly extracted from infected Aedes aegypti Liverpool strain (LVP) mosquitoes are strongly attracted to both fetal bovine serum (FBS) and sodium chloride but are weakly repelled by 3-methyl-1-butanol (a component of human sweat attractive to S. …

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  • Fonsecaea pedrosoi conidia and hyphae activate

    2020-1-6u2002·u2002was collected using fetal bovine serum-free RPMI medium. The cells were passed through a cell strainer to retain the small debris and clots. The cells were washed once in 1x PBS and neutrophil enrichment was performed using a Ficoll density layer (1119 and made available under aCC-BY 4.0 International license.

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  • Cytiva

    Cytiva is a global provider of technologies and services that help advance and accelerate the development and manufacture of therapeutics. With a heritage of innovation, they continue to move forward, building on the brands you've come to rely on for quality and reliability. Their diverse portfolio includes the well-recognized ÄKTA ...

    Get Price
  • Lipid Nanoparticle Formulation Increases Efficiency of DNA ...

    2020-5-29u2002·u2002Using 96 well plates, serum was heat inactivated (56 °C for 30 minutes) and diluted in MEM containing 5% heat inactivated fetal bovine serum (FBS). ZIKV was added to each well to a final ...

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  • BÜCHI Labortechnik

    2021-10-2u2002·u2002BUCHI NIR-Online® launches a new sensor for essential process control 2021 Jul. 12. Flawil, Switzerland, July 12, 2021 – With the launch of the NIR-Online X-Sential™, BÜCHI Labortechnik AG introduces a new process sensor that takes advantage of more than 15 years of in-the-field experience with process NIR technology and applicati

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  • Laboratory Freezers

    2021-9-30u2002·u2002Premier Plus Series Auto Defrost -30°C Freezer. High-performance laboratory freezers are designed for applications requiring storage of reagents, pharmaceuticals, biological and other commonly used laboratory materials such as primers, siRNA molecules and fetal bovine serum (FBS).

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  • Lab-grown meat is supposed to be inevitable. The science ...

    2021-9-23u2002·u2002Lab-grown meat is supposed to be inevitable. The science tells a different story. Splashy headlines have long overshadowed inconvenient truths about biology and economics. Now, extensive new research suggests the industry may be on a billion-dollar crash course with reality.

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  • Colostrum Supplements and Replacer - Penn State Extension

    2016-5-5u2002·u2002Any product that is able to raise serum IgG concentration above 10 mg/mL may be called a colostrum replacer. Colostrum supplements available today are made from dried bovine colostrum or serum and contain 40 to 60 g of IgG per dose (9 to 13% globulin protein). The fat content of these products ranges from 0.5 to 15%.

    Get Price
  • Cytiva

    Cytiva is a global provider of technologies and services that help advance and accelerate the development and manufacture of therapeutics. With a heritage of innovation, they continue to move forward, building on the brands you've come to rely on for quality and reliability. Their diverse portfolio includes the well-recognized ÄKTA ...

    Get Price
  • Platelet lysate as a substitute for animal serum for the ...

    2016-7-13u2002·u2002The use of fetal bovine serum (FBS) as a cell culture supplement is discouraged by regulatory authorities to limit the risk of zoonoses and xenogeneic immune reactions in the transplanted host. Additionally, FBS production came under scrutiny due to animal welfare concerns. Platelet derivatives have been proposed as FBS substitutes for the ex-vivo expansion …

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  • BLIRT - Manufacturer of recombinant enzymes & proteins

    2021-10-1u2002·u2002Founded in 1994, BLIRT is a primary European manufacturer of recombinant enzymes for the Life Science industry. The motto of Enzymes As You Need reflects both our business philosophy and the reasonable offer for B2B partners. We focus on providing components – enzymes for customers' innovative products and additional portioning services ...

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  • Effects of embryo-derived exosomes on the development of ...

    2017-3-28u2002·u2002Briefly, bovine cumulus–oocyte complexes (COCs) were aspirated from 2 mm to 8 mm antral follicles of ovaries obtained from Tumen abattoir in Xi'an, Shaanxi, China, and were washed thrice in phosphate-buffered saline (PBS) supplemented with 5% (v/v) fetal bovine serum (FBS).

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  • Rapid Large-Scale Expansion of Functional Mesenchymal Stem ...

    2008-9-9u2002·u2002This study was performed to develop conditions for regularly propagating a clinical quantity of >2 × 10 8 MSCs without animal serum from small bone marrow (BM) aspiration volumes within short time. We established optimized culture conditions with pooled human platelet lysate (pHPL) replacing fetal bovine serum (FBS) for MSC propagation.

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  • Overview of Selenium Toxicosis - Toxicology - Merck ...

    Overview of Selenium Toxicosis. Selenium is an essential element that has a narrow margin of safety, with the difference between adequate and potentially toxic concentrations in the diet being approximately 10- to 20-fold. Feed supplements, resulting in final selenium content of 0.2–0.3 ppm, are added to diets to prevent deficiency and ...

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  • Why cows are getting a bad rap in lab-grown meat debate ...

    2018-10-31u2002·u2002A typical growth medium contains an energy source such as glucose, synthetic amino acids, antibiotics, fetal bovine serum, horse serum and chicken embryo extract. If cultured meat is to match or exceed the nutritional value of conventional meat products, nutrients found in meat not synthesized by muscle cells must be supplied as supplements in ...

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  • Transplantation of Allogenic Fetal Membrane-Derived ...

    2014-7-1u2002·u2002PGE2 enhanced the secretion of IL-10 from immune cells, and so we measured serum IL-10 levels and found a significant increase in IL-10 in the FM-MSC group at 24 h after reperfusion (113.0 ± 13.2 pg/ml), while serum IL-10 was not detected in PBS-treated group. Therefore, we attempted to confirm if IL-10 is a key mediator in this model.

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  • FROM LAB TO FORK

    2021-4-29u2002·u2002replacement products is raising new concerns. Significant investment has been made in the research and de-velopment of non-plant based products in an attempt to mimic animal-based products, ranging from animal tissue grown from animal cell cultures made with animal serum, to proteins produced by genetically engi-neered algae and yeast.

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