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  • Nanoparticle‐mediated delivery of superoxide dismutase

    superoxide dismutase to the brain: an effective strat-egy to reduce ischemia-reperfusion injury. FASEB J. 23, 1384–1395 (2009) Key Words: antioxidant enzymes blood-brain barrier biode-gradable polymers sustained release nanomedicine Thromboembolic stroke is common among acute ischemic strokes and is the major cause of death and

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  • Superoxide Dismutase Archives - Randox Laboratories

    2016-10-20u2002·u2002Superoxide Dismutase. Superoxide is a by-product of oxygen metabolism and is one of the most damaging free radicals in the body as it can cause cell damage. Superoxide Dismutase (SOD) is an enzyme which catalyses the breakdown of superoxide into a less damaging oxygen or hydrogen peroxide.

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  • Boron influences immune and antioxidant responses by ...

    2016-7-1u2002·u20021. Introduction. Boron (B) is a newer trace element for animals and its biological importance and dietary essentiality is unclear. Limited research conducted across the world indicates a putative role of B in various physiological functions, especially in improving the utilization of bone forming minerals like calcium (Ca), phosphorus (P) and magnesium (Mg), …

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  • Superoxide Dismutase Assay Kit - Cayman Chemical

    The Cayman Chemical SOD Assay kit is a fast and reliable assay for the measurement of SOD activity from plasma, serum, tissue homogenates, and cell lysates. SOD activity is assessed by measuring the dismutation of superoxide radicals generated by xanthine oxidase and hypoxanthine in a convenient 96 well format.

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  • PLT to distribute GliSODin - NutraIngredients

    2002-6-6u2002·u2002According to the company, superoxide dismutase is a master defence enzyme and powerhouse antioxidant which occurs naturally in human cells. The production of SOD in the body decreases during the ageing process. GliSODin is derived from melons, although a previous source was bovine liver.

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  • A new recombinant MS-superoxide dismutase alleviates 5 ...

    2019-9-10u2002·u2002The administration of exogenous superoxide dismutase (SOD) can eliminate ROS produced in the initial stage of mucosal injury, thereby improving or delaying injury; therefore, SOD is a potential ...

    Get Price
  • The impact of Achyranthes aspera seeds and leaves ...

    The present study was conducted to evaluate the effect of dietary inclusion of Achyranthes aspera seeds and leaves on the immune system of magur Clarias batrachus challenged with Aeromonas hydrophila in pond conditions. Magur fry (0.51 ± 0.032 g) were cultured in hapas set inside a pond and were fed with three feeds.

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  • Nutraceutical effect of minerals on performance, immunity ...

    2019-7-30u2002·u2002The aim of this study was to evaluate whether the use of a mineral complex improves the performance and health of suckling piglets in the maternity phase. Three groups were formatted as follows: control group T1, administration of parenteral minerals on day of birth T2 (0.1 mL of piglet), and 3 days after birth T3 (0.1 mL of piglet). The body weight and blood samples …

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  • Myocardial Protective Effect of Extracellular Superoxide ...

    2014-2-15u2002·u2002Extracellular superoxide dismutase (ecSOD) binds to heparin sulfate proteoglycans on cellular surface as a unique scavenger of superoxide anions in the extracellular space . Many studies have shown that direct gene transfer of the cDNA encoding membrane-bound human ecSOD affords transient cardio-protective effect [ 3, 5 ].

    Get Price
  • A new recombinant MS-superoxide dismutase alleviates 5 ...

    2019-9-10u2002·u2002The administration of exogenous superoxide dismutase (SOD) can eliminate ROS produced in the initial stage of mucosal injury, thereby improving or delaying injury; therefore, SOD is a potential ...

    Get Price
  • Effects of plant essential oil supplementation on growth ...

    2018-6-15u2002·u2002The aim of this study was to determine the effects of plant essential oil supplementation on growth performance, immune function and antioxidant activities in weaned pigs. In the study, 24 weaned pigs were used to explore the effects of plant essential oil (PEO) on growth performance, immune properties and antioxidant activities. Pigs were fed with a basal diet (CON) or basal diet containing ...

    Get Price
  • Protection of Bovine Mammary Epithelial Cells from ...

    The mammary epithelial cells (MECs) of high-producing dairy cows are likely to be subject to oxidative stress (OS) due to the intensive cell metabolism. The objectives of this study were to investigate the cytoprotective effects of resveratrol against hydrogen peroxide- (H 2 O 2 -) induced OS in cultured bovine …

    Get Price
  • Inflammatory Biomarker Series: Antioxidants - Randox ...

    2017-2-21u2002·u2002Inflammatory Biomarker Series: Antioxidants. So far in our inflammatory biomarker series, we have considered the clinical significance of measuring rheumatoid factor (RF) and C-reactive protein (CRP) to detect inflammation. Inflammation, either chronic or acute, is the body's immune response to protect against harmful stimuli such as damaged ...

    Get Price
  • Nutraceutical effect of minerals on performance, immunity ...

    2019-7-30u2002·u2002The aim of this study was to evaluate whether the use of a mineral complex improves the performance and health of suckling piglets in the maternity phase. Three groups were formatted as follows: control group T1, administration of parenteral minerals on day of birth T2 (0.1 mL of piglet), and 3 days after birth T3 (0.1 mL of piglet). The body weight and blood samples were analyzed at birth and ...

    Get Price
  • Impacts of selenium and vitamin E supplementation on

    2018-7-10u2002·u2002The study was carried out to investigate the effect of dietary selenium (Se) and vitamin E (VE) supplementation on mRNA level of heat shock proteins, selenoproteins, and antioxidant enzyme activities in the breast meat of broilers under summer heat stress conditions. A total of 200 male broilers (Ross 308) of 1 day age were randomly separated into 4 groups in a complete randomized design and ...

    Get Price
  • Ginsenoside Rb3 ameliorates myocardial ischemia ...

    2018-11-9u2002·u2002et al., 1951) using bovine serum albumin as standard. The determination of malonyldialdehyde (MDA) content in left ventricles was performed according to the previous method (Ohkawa et al., 1979).Superoxide dismutase (SOD) activity was determined by the nitroblue tetrazo-lium reduction method (McCord & Fridovich, 1969). Statistical analysis

    Get Price
  • Health benefits of milk and functional dairy products

    2017-1-26u2002·u2002benefits that are the direct antitheses of diseases and complexity that related to overweight and obesity. For example, individuals that consume dairy products are more likely to have lower weight,4 lower blood pressure,5,6 and decreased risk of stroke, colon cancer7–9 and osteoporosis.10,11 There is a wide range of functional foods that were

    Get Price
  • Biology

    High-fat (HF) meal-induced postprandial lipemia, oxidative stress and low-grade inflammation is exacerbated in overweight and obese individuals. This postprandial dysmetabolism contributes to an increased risk of cardiovascular disease and metabolic disorders. Clitoria ternatea flower extract (CTE) possesses antioxidant potential and carbohydrate and fat digestive enzyme inhibitory activity in ...

    Get Price
  • Myocardial Protective Effect of Extracellular Superoxide ...

    2014-2-15u2002·u2002Extracellular superoxide dismutase (ecSOD) binds to heparin sulfate proteoglycans on cellular surface as a unique scavenger of superoxide anions in the extracellular space . Many studies have shown that direct gene transfer of the cDNA encoding membrane-bound human ecSOD affords transient cardio-protective effect [ 3, 5 ].

    Get Price
  • A new recombinant MS-superoxide dismutase alleviates 5 ...

    2019-9-10u2002·u2002The administration of exogenous superoxide dismutase (SOD) can eliminate ROS produced in the initial stage of mucosal injury, thereby improving or delaying injury; therefore, SOD is a potential ...

    Get Price
  • Effects of plant essential oil supplementation on growth ...

    2018-6-15u2002·u2002The aim of this study was to determine the effects of plant essential oil supplementation on growth performance, immune function and antioxidant activities in weaned pigs. In the study, 24 weaned pigs were used to explore the effects of plant essential oil (PEO) on growth performance, immune properties and antioxidant activities. Pigs were fed with a basal diet (CON) or basal diet containing ...

    Get Price
  • Protection of Bovine Mammary Epithelial Cells from ...

    The mammary epithelial cells (MECs) of high-producing dairy cows are likely to be subject to oxidative stress (OS) due to the intensive cell metabolism. The objectives of this study were to investigate the cytoprotective effects of resveratrol against hydrogen peroxide- (H 2 O 2 -) induced OS in cultured bovine …

    Get Price
  • Inflammatory Biomarker Series: Antioxidants - Randox ...

    2017-2-21u2002·u2002Inflammatory Biomarker Series: Antioxidants. So far in our inflammatory biomarker series, we have considered the clinical significance of measuring rheumatoid factor (RF) and C-reactive protein (CRP) to detect inflammation. Inflammation, either chronic or acute, is the body's immune response to protect against harmful stimuli such as damaged ...

    Get Price
  • Nutraceutical effect of minerals on performance, immunity ...

    2019-7-30u2002·u2002The aim of this study was to evaluate whether the use of a mineral complex improves the performance and health of suckling piglets in the maternity phase. Three groups were formatted as follows: control group T1, administration of parenteral minerals on day of birth T2 (0.1 mL of piglet), and 3 days after birth T3 (0.1 mL of piglet). The body weight and blood samples were analyzed at birth and ...

    Get Price
  • Impacts of selenium and vitamin E supplementation on

    2018-7-10u2002·u2002The study was carried out to investigate the effect of dietary selenium (Se) and vitamin E (VE) supplementation on mRNA level of heat shock proteins, selenoproteins, and antioxidant enzyme activities in the breast meat of broilers under summer heat stress conditions. A total of 200 male broilers (Ross 308) of 1 day age were randomly separated into 4 groups in a complete randomized design and ...

    Get Price
  • Ginsenoside Rb3 ameliorates myocardial ischemia ...

    2018-11-9u2002·u2002et al., 1951) using bovine serum albumin as standard. The determination of malonyldialdehyde (MDA) content in left ventricles was performed according to the previous method (Ohkawa et al., 1979).Superoxide dismutase (SOD) activity was determined by the nitroblue tetrazo-lium reduction method (McCord & Fridovich, 1969). Statistical analysis

    Get Price
  • Health benefits of milk and functional dairy products

    2017-1-26u2002·u2002benefits that are the direct antitheses of diseases and complexity that related to overweight and obesity. For example, individuals that consume dairy products are more likely to have lower weight,4 lower blood pressure,5,6 and decreased risk of stroke, colon cancer7–9 and osteoporosis.10,11 There is a wide range of functional foods that were

    Get Price
  • Biology

    High-fat (HF) meal-induced postprandial lipemia, oxidative stress and low-grade inflammation is exacerbated in overweight and obese individuals. This postprandial dysmetabolism contributes to an increased risk of cardiovascular disease and metabolic disorders. Clitoria ternatea flower extract (CTE) possesses antioxidant potential and carbohydrate and fat digestive enzyme inhibitory activity in ...

    Get Price
  • Myocardial Protective Effect of Extracellular Superoxide ...

    2014-2-15u2002·u2002Extracellular superoxide dismutase (ecSOD) binds to heparin sulfate proteoglycans on cellular surface as a unique scavenger of superoxide anions in the extracellular space . Many studies have shown that direct gene transfer of the cDNA encoding membrane-bound human ecSOD affords transient cardio-protective effect [ 3, 5 ].

    Get Price
  • A new recombinant MS-superoxide dismutase alleviates 5 ...

    2019-9-10u2002·u2002The administration of exogenous superoxide dismutase (SOD) can eliminate ROS produced in the initial stage of mucosal injury, thereby improving or delaying injury; therefore, SOD is a potential ...

    Get Price
  • Effects of plant essential oil supplementation on growth ...

    2018-6-15u2002·u2002The aim of this study was to determine the effects of plant essential oil supplementation on growth performance, immune function and antioxidant activities in weaned pigs. In the study, 24 weaned pigs were used to explore the effects of plant essential oil (PEO) on growth performance, immune properties and antioxidant activities. Pigs were fed with a basal diet (CON) or basal diet containing ...

    Get Price
  • Protection of Bovine Mammary Epithelial Cells from ...

    The mammary epithelial cells (MECs) of high-producing dairy cows are likely to be subject to oxidative stress (OS) due to the intensive cell metabolism. The objectives of this study were to investigate the cytoprotective effects of resveratrol against hydrogen peroxide- (H 2 O 2 …

    Get Price
  • Inflammatory Biomarker Series: Antioxidants - Randox ...

    2017-2-21u2002·u2002Inflammatory Biomarker Series: Antioxidants. So far in our inflammatory biomarker series, we have considered the clinical significance of measuring rheumatoid factor (RF) and C-reactive protein (CRP) to detect inflammation. Inflammation, either chronic or acute, is the body's immune response to protect against harmful stimuli such as damaged ...

    Get Price
  • Nutraceutical effect of minerals on performance, immunity ...

    2019-7-30u2002·u2002The aim of this study was to evaluate whether the use of a mineral complex improves the performance and health of suckling piglets in the maternity phase. Three groups were formatted as follows: control group T1, administration of parenteral minerals on day of birth T2 (0.1 mL of piglet), and 3 days after birth T3 (0.1 mL of piglet). The body weight and blood samples were analyzed at birth and ...

    Get Price
  • Impacts of selenium and vitamin E supplementation on

    2018-7-10u2002·u2002The study was carried out to investigate the effect of dietary selenium (Se) and vitamin E (VE) supplementation on mRNA level of heat shock proteins, selenoproteins, and antioxidant enzyme activities in the breast meat of broilers under summer heat stress conditions. A total of 200 male broilers (Ross 308) of 1 day age were randomly separated into 4 groups in a complete randomized design and ...

    Get Price
  • Ginsenoside Rb3 ameliorates myocardial ischemia ...

    2018-11-9u2002·u2002et al., 1951) using bovine serum albumin as standard. The determination of malonyldialdehyde (MDA) content in left ventricles was performed according to the previous method (Ohkawa et al., 1979).Superoxide dismutase (SOD) activity was determined by the nitroblue tetrazo-lium reduction method (McCord & Fridovich, 1969). Statistical analysis

    Get Price
  • Health benefits of milk and functional dairy products

    2017-1-26u2002·u2002benefits that are the direct antitheses of diseases and complexity that related to overweight and obesity. For example, individuals that consume dairy products are more likely to have lower weight,4 lower blood pressure,5,6 and decreased risk of stroke, colon cancer7–9 and osteoporosis.10,11 There is a wide range of functional foods that were

    Get Price
  • Biology

    High-fat (HF) meal-induced postprandial lipemia, oxidative stress and low-grade inflammation is exacerbated in overweight and obese individuals. This postprandial dysmetabolism contributes to an increased risk of cardiovascular disease and metabolic disorders. Clitoria ternatea flower extract (CTE) possesses antioxidant potential and carbohydrate and fat digestive enzyme inhibitory activity in ...

    Get Price
  • Placental superoxide dismutase 3 mediates benefits of ...

    Kusuyama et al. define a novel mechanism for placental transmission of improved metabolic health to offspring. SOD3 is identified as an exercise-induced and vitamin D-regulated placenta-derived protein that improves glucose homeostasis in offspring. SOD3 activates an AMPK/TET signaling axis resulting in epigenetic changes to metabolic genes in offspring liver.

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  • circ-PRKCB acts as a ceRNA to regulate p66Shc-mediated ...

    2020-8-29u2002·u2002Abstract. Background: Oxidative stress has emerged as an essential factor in the pathogenesis of intestinal ischemia/reperfusion (I/R) injury. The adaptor protein p66Shc is a key regulator of reactive oxygen species (ROS) generation and a mediator of I/R damage in the intestine, but the upstream mechanisms that directly regulate p66Shc expression during …

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  • Potential of crocodile blood as a medication and dietary ...

    2021-5-13u2002·u20021 INTRODUCTION. Long before the recent popularity of crocodile blood, various crocodile organs have been used since ancient times as folk medicines to treat disease, such as asthma and allergies. 1, 2 Recently in 2003, Dr. Merchant's group began extensive research on the antimicrobial and antiviral activities of alligator blood; 3-5 later expanding to other species of …

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  • Antioxidant and C5a-blocking strategy for hepatic ischemia ...

    2021-4-15u2002·u2002Nonspecific liver uptake of nanomaterials after intravenous injection has hindered nanomedicine for clinical translation. However, nanomaterials' propensity for liver distribution might enable their use in hepatic ischemia–reperfusion injury (IRI) repair. During hepatic IRI, reactive oxygen species (ROS) are generated and the fifth component of complement (C5a) is activated.

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  • Frontiers

    Diabetes has become the second most severe disease to human health. Probiotics are important for maintaining gastrointestinal homeostasis and energy balance and have been demonstrated to play a positive role in the prevention and treatment of metabolic syndromes, such as obesity, inflammation, dyslipidemia, and hyperglycemia. The objective of this study was to screen …

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  • Dietary L-citrulline supplementation modulates nitric ...

    2020-10-12u2002·u2002L-citrulline (L-Cit), a non-protein amino acid, has been implicated in several physiological functions including anti-inflammatory, anti-oxidative, and hypothermic roles, however, there is a paucity of information with regards to its potential in poultry production. This study was designed to investigate the effects of dietary L-Cit supplementation on the production …

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  • A Safe, Non-Drug, Natural Approach to Attention Deficit ...

    Scores of published human studies, including double-blind clinical trials, establish that Flavay Plus® increases blood flow, improves nitric oxide levels and neurotransmitter activities, improves glucose metabolism in brain cells (all of which is essential to learning, memory and other cognitive functions) and thereby:. strengthens memory, (168, 126, 213)

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  • Effect of the flavonoid baicalin on the proliferative ...

    2021-9-19u2002·u2002Background High-yielding dairy cows are prone to oxidative stress due to the high metabolic needs of homeostasis and milk production. Oxidative stress and inflammation are tightly linked; therefore, anti-inflammatory and/or natural antioxidant compounds may help improve mammary cell health. Baicalin, one of the major flavonoids in Scutellaria baicalensis, has natural …

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  • Triptolide ameliorates fine particulate matter-induced ...

    2020-2-3u2002·u2002Background PM2.5 is associated closely with an increased risk of membranous nephropathy (MN), however, whether PM2.5 could induce podocytes injury, the underlying pathology for MN, has not be thoroughly studied. Triptolide, an active component in Tripterygium wilfordii Hook F, is frequently used to treat MN in China, but its effects on PM2.5-induced …

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  • (PDF) Normalizing Mitochondrial Superoxide Production ...

    mitochondrial superoxide. Our results show that a single unify ing mechanism of induction, increased production of superoxide by the mitochondrial electron. transport chain, is a causal link ...

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  • Peripartal rumen-protected methionine supplementation

    2016-3-9u2002·u2002Main objectives were to determine to what extent Smartamine M (SM) supplementation to a prepartal higher-energy diet could alter neutrophil (PMN) and liver tissue immunometabolic biomarkers, and whether those responses were comparable to those in cows fed a prepartal lower-energy diet (CON). Twenty-eight multiparous Holstein cows were fed CON (NEL = 1.24 Mcal/kg DM) during d −50 to d …

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  • Hypoglycaemic effect of galactooligosaccharides in alloxan ...

    GOS was also found to improve the levels of antioxidative enzymes (superoxide dismutase, catalase and glutathione peroxidase) in liver and blood. Improvement in lactobacilli count along with a concomitant decrease in coliform count was observed in GOS fed groups.

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  • Oxidative and nitrosative stress in acute renal ischemia ...

    2001-11-1u2002·u2002First Published July 12, 2001; 10.1152/ajprenal.0071.2001.—Generation of reactive oxygen species and nitric oxide in hypoxia-reperfusion injury may form a cytotoxic metabolite, peroxynitrite, which is capable of causing lipid peroxidation and DNA damage. This study was designed to examine the contribution of oxidative and nitrosative stress to the renal damage in ischemic acute renal failure ...

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  • Two Vaccines for Staphylococcus aureus Induce a B-Cell ...

    2018-8-22u2002·u2002Staphylococcus aureus causes severe disease in humans for which no licensed vaccine exists. A novel S. aureus vaccine (SA4Ag) is in development, targeting the capsular polysaccharides (CPs) and two virulence-associated surface proteins. Vaccine-elicited antibody responses to CPs are efficacious against serious infection by other encapsulated bacteria. Studies of natural S. aureus …

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  • Glutathione peroxidase 4 prevents necroptosis in mouse ...

    2016-1-7u2002·u2002Due to their physiological function in oxygen transport, oxygen-loaded erythrocytes are under constant oxidative stress. Thus, erythrocytes are equipped with a battery of antioxidant enzymes that supports dismutation of superoxide radicals, detoxification of hydrogen and lipid peroxides, and maintenance of a reducing intracellular milieu (eg, superoxide dismutase 1 and 2, catalase, glutathione ...

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  • Jugular infusion of arginine has a positive effect on ...

    2018-8-20u2002·u2002Blood Sampling and Analyses. g, at 4 °C for 10 min) 2 h after collection and a portion of serum was stored at −20 °C for the analysis of growth hormone, insulin, and prolactin. Then, a portion of serum aliquot (0, 3, and 6 h) in each period for each cow was pooled prior to storage at −20 °C for the analysis of total antioxidant capacity ...

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  • FAQ Continued page 2 of 2 – Suzy Cohen

    A: Superoxide dismutase (S.O.D.) is an enzyme that has powerful effects on the skin, and is a liver-generated enzyme in the human body. The supplemental form of S.O.D. that is in DermaScript is actually derived from a fruit, specifically melons, but there are no fruit extracts or melons in the finished formula.

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  • (PDF) Normalizing Mitochondrial Superoxide Production ...

    mitochondrial superoxide. Our results show that a single unify ing mechanism of induction, increased production of superoxide by the mitochondrial electron. transport chain, is a causal link ...

    Get Price
  • Sodium butyrate improves antioxidant stability in sub ...

    2018-9-10u2002·u2002Currently, little is known about the effect of sodium butyrate (NaB) on oxidative stress following grain-induced sub-acute ruminal acidosis in dairy goats. In the present study, 18 lactating dairy goats implanted with a ruminal cannula and permanent indwelling catheters in the portal and hepatic veins were randomly allocated into 3 treatment groups over 20 weeks: low grain (LG, 40% grain; n ...

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  • The role of mesenchymal stem cells in chemotherapy

    2018-7-18u2002·u2002The therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-MSCs) against cisplatin-induced nephrotoxicity has been reported, however, its efficacy in gonadotoxicity still has not been addressed. Herein, we investigated the effect of BM-MSCs in cisplatin-induced testicular toxicity and its underlying mechanism of action. Thirty male Sprague–Dawley rats were divided into a ...

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